Phospho-Bad (Ser112) (40A9) Rabbit mAb 5284S from Cell Signaling Technology

Product Specs
ItemPhospho-Bad (Ser112) (40A9) Rabbit mAb
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number5284S
Quantity100 µl
ApplicationsW, W-S, IHC-P, FC-FP
ReactivityH, M, R, Mk
TargetBad (Ser75) phosphate
ModificationsBad (Ser112) phosphate mouse
HostRabbit
NCBI Gene AliasesBBC2, BCL2L8
ClonalityMonoclonal
NCBI Full Gene NameBCL2 associated agonist of cell death
Research AreaApoptosis
Clone40A9
Molecular Weight23

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) Non-small cell lung cancers (NSCLCs) oncolysis using coxsackievirus B5 and synergistic DNA-damage response inhibitorsSignal Transduction and Targeted TherapySeptember 25, 2023Bopei Cui, Lifang Song, Qian Wang, Kelei Li, Qian He, Xing Wu, Fan Gao, Mingchen Liu, Chaoqiang An, Qiushuang Gao, et al.Cell Signaling Technology), p-Bad (Ser136, 1: 1000, 4366, Cell Signaling Technology), p-Bad (Ser112,1: 1000, 5284, Cell Signaling Technology), Bax (1: 1000, 5023, Cell Signaling Technology), Bcl-2 (1: 1000, 3498, Cell Signaling Technology

(2) Dual role of PID1 in regulating apoptosis induced by distinct anticancer-agents through AKT/Raf-1-dependent pathway in hepatocellular carcinomaCell death discoveryApril 28, 2023Yang J, Li S, He J, Xu Q, Xie M, Yang C, Wang H, Zhang Y, Wan Q, Xiang M.USA), Bcl2 (#12789-1-AP; Proteintech), BAD (#sc-8044 Santa Cruz Technology, Texas, USA), p-BADS112 (#5284; Cell Signaling Technology), p-BADS136 (#4366; Cell Signaling Technology), cytochrome c (#sc-13156;

(3) Renoprotective effect of Tanshinone IIA against kidney injury induced by ischemia-reperfusion in obese ratsAgingOctober 20, 2022Tai H, Cui XZ, He J, Lan ZM, Li SM, Li LB, Yao SC, Jiang XL, Meng XS, Kuang JS.KDa,"1:10,000" Anti-Akt,Proteintech,10176-2-AP,56 KDa,"1:5,000" Anti-p-Bad,Cell Signaling Technology,5284S,23 KDa,"1:1,000" Anti-Bad,Proteintech,10435-1-AP,18 KDa,"1:2,500" Anti-Bcl-2,Proteintech,26593-1-AP,26

(4) Structure of the SHOC2–MRAS–PP1C complex provides insights into RAF activation and Noonan syndromeNature Structural & Molecular BiologyOctober 1, 2022Daniel A. Bonsor, Patrick Alexander, Kelly Snead, Nicole Hartig, Matthew Drew, Simon Messing, Lorenzo I. Finci, Dwight V. Nissley, Frank McCormick, Dominic Esposito, et al.pS365 BRAF (in-house antibody, 1:1,000 dilution), pS259 CRAF (CST no. 9421 1:2,000), BRAF F7 (SC no. 5284, 1:6,000 dilution), CRAF (BD no. 610152, 1:10,000 dilution), SHOC2 (in-house antibody, 1:10,000 dilution),

(5) Potential Biochemical Pesticideâ€”Synthesis of Neofuranocoumarin and Inhibition the Proliferation of Spodoptera frugiperda Cells through Activating the Mitochondrial PathwayToxins (Basel)September 29, 2022Xuehua Shao, Zhuhong Zhang, Xuhong Qian, Lanying Wang, Yunfei Zhang, Yanping Luo(Beyotime, Beijing, China). Phosphor-Akt (Ser473) rabbit mAb (#4060), Phosphor-Bad (Ser112) rabbit mAb (#5284), Cleaved PARP (Asp214) rabbitAb (#5625), Akt antibody (#9272), p53 rabbit mAb (#2527), Cytochrome C

(6) Antagonistic roles of Ras-MAPK and Akt signaling in Integrin-K+ channel Complexes-mediated cellular apoptosisThe FASEB JournalSeptember 29, 2022Elena Forzisi, Wei Yu, Parth Rajwade, Federico Sesti#3285), phospho-FAK (Tyr576/577 cat #3281), phospho-Bad (Ser136, cat. #4366), phospho-Bad (Ser112, cat. #5284), Akt (cat. #9272) and phospho-Akt (ser 473 cat. #9271) were purchased from Cell Signaling Technologies

(7) Regulation of Stress-Activated Kinases in Response to Tacaribe Virus Infection and Its Implications for Viral ReplicationVirusesSeptember 12, 2022Holzerland J, Fénéant L, Groseth A.detect Caspase 3 (#9662; 1:1000/1:500 [full-length/cleaved]), Bad (#9239; 1:500), phospho-Bad (Ser112) (#5284; 1:500), Erk (#4695; 1:1000), phospho-Erk (#9101; 1:1000), Akt (#9272; 1:1000), phospho-Akt (#4060;

(8) Inhibition of Glutamine Uptake Resensitizes Paclitaxel Resistance in SKOV3-TR Ovarian Cancer Cell via mTORC1/S6K Signaling PathwayInternational Journal of Molecular SciencesAugust 6, 2022Gyeongmi Kim, Se-Kyeong Jang, Yu Jin Kim, Hyeon-Ok Jin, Seunghee Bae, Jungil Hong, In-Chul Park, Jae Ho Lee(#2217), p-S6 (Ser240/244) (#5364), p-Bcl-2 (#2827), Bcl-2 (#150071), Bcl-XL (#2764), Bax (#2772), p-Bad (#5284), Bad (#9292), Bid (#2002), Bak (#12105), and Mcl-1 (#5453), all of which were obtained from Cell Signaling Technology

(9) Deficiency of kin17 Facilitates Apoptosis of Cervical Cancer Cells by Modulating Caspase 3, PARP, and Bcl-2 Family ProteinsJournal of OncologyJuly 20, 2022Bingsen Su, Meifeng Zhong, Yuzhao Zhang, Kunhe Wu, Qiyuan Huang, Chuiyu Zhu, Tao Zenganti-BAD (dilution, 1 : 1000; #9239; Cell Signaling Technology, Inc.), anti-p-BAD (dilution, 1 : 1000; #5284; Cell Signaling Technology, Inc.), and anti-GAPDH (dilution, 1 : 500; sc-47778; Santa Cruz Biotechnology, Inc

(10) A possible new activator of PI3K-Huayu Qutan Recipe alleviates mitochondrial apoptosis in obesity rats with acute myocardial infarctionJournal of cellular and molecular medicineJune 1, 2022Tai H, Tong YJ, Yu R, Yu Y, Yao SC, Li LB, Liu Y, Cui XZ, Kuang JS, Meng XS, et al.KDa,"1:10,000" Anti‐Akt,Proteintech,10176‐2‐AP,56 KDa,1:5000 Anti‐p‐Bad,Cell signaling technology,5284S,23 KDa,1:1000 Anti‐Bad,Proteintech,10435‐1‐AP,18 KDa,1:2500 Anti‐Bcl‐2,Proteintech,26593‐1‐AP,26 KDa,1:2500 Anti‐Bax,Proteintech,50599‐2‐1g,26

(11) MYSM1 induces apoptosis and sensitizes TNBC cells to cisplatin via RSK3-phospho-BAD pathwayCell death discoveryFebruary 26, 2022Guan X, Meng X, Zhu K, Kai J, Liu Y, Ma Q, Tong Y, Zheng H, Xie S, Ma X, et al.Cell Signaling Technology, USA), Caspase-9 (9508, 1:1000, Cell Signaling Technology, USA), and phospho-BAD (Ser 112) (5284, 1:500, Cell Signaling Technology, USA), BAD (9239, 1:500, Cell Signaling Technology, USA). The secondary

(12) ZDHHC22-mediated mTOR palmitoylation restrains breast cancer growth and endocrine therapy resistanceInternational journal of biological sciencesJanuary 1, 2022Huang J, Li J, Tang J, Wu Y, Dai F, Yi Z, Wang Y, Li Y, Wu Y, Ren G, et al.ab71973, Abcam), anti-phospho-AKT (T308) (1:100, sc-271966, Santa Cruz), anti-phospho-BAD (1:1000, #5284, Cell Signaling Technology), anti-phospho- GSK3β(Ser9) (1:1,000, #9323, Cell Signaling Technology),

(13) P90 ribosomal S6 kinase confers cancer cell survival by mediating checkpoint kinase 1 degradation in response to glucose stressCancer ScienceJanuary 1, 2022Ying Ma, Danrui Cui, Linchen Wang, Yue Wang, Fei Yang, Hui Pan, Longyuan Gong, Minrun Zhang, Xiufang Xiong, Yongchao Zhaofor immunohistochemistry (ab47574; Abcam), p‐CHK1 Ser280 (2347), p‐AMPK Thr172 (2535), AMPK (5831), p‐BAD Ser112 (5284), BAD (9239), caspase‐3 (9665), p‐GSK3β Ser9 (9323), GSK3α/β (5676), PARP (9542), p‐ERK Thr202/Tyr204

(14) TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalanOncotargetOctober 12, 2021Håland E, Moen IN, Veidal E, Hella H, Misund K, Slørdahl TS, Starheim KK.phospho-Ser1981 (Cell Signaling Technologies (CST), Danvers, MA, USA, 5883), Bad phospho-Ser112 (CST, 5284), Bad (CST, 9239), Bak (CST, 12105), Bax (CST, 5023), BID (CST, 2002), Bim (CST, 2933), β-tubulin (Abcam,

(15) Erk phosphorylation reduces the thymoquinone toxicity in human hepatocarcinomaEnvironmental ToxicologyOctober 1, 2021Bin Zhang, Wei‐Jen Ting, Jun Gao, Zhan‐Fang Kang, Chih‐Yang Huang, Yi‐Jiun WengMA) including against Erk (#4695), p‐Erk (#4370), p38 (#8690), p‐p38 (#4511), Bad (#9239), p‐Bad (#5284), 14–3‐3 (#9636), cleaved caspase‐3 (# 9664), and GAPDH (#5174) at 4 °C overnight. After soaking in

(16) Non-Canonical Role of PDK1 as a Negative Regulator of Apoptosis through Macromolecular Complexes Assembly at the ER–Mitochondria Interface in Oncogene-Driven NSCLCCancers (Basel)August 17, 2021Viviana De Rosa, Francesca Iommelli, Cristina Terlizzi, Eleonora Leggiero, Rosa Camerlingo, Giovanna G. Altobelli, Rosa Fonti, Lucio Pastore, Silvana Del VecchioHexokinase II (2867, Cell Signaling Technology), LDH-A (3582, Cell Signaling Technology), p-BADSer112 (5284, Cell Signaling Technology), cleaved caspase 3 (9661, Cell Signaling Technology) and BAX (5023, Cell Signaling Technology

(17) LY‑294002 enhances the chemosensitivity of liver cancer to oxaliplatin by blocking the PI3K/AKT/HIF‑1α pathwayMolecular medicine reportsJuly 1, 2021Xu R, Zhang Y, Li A, Ma Y, Cai W, Song L, Xie Y, Zhou S, Cao W, Tang X.no. 4292), Akt (cat. no. 4691), p‑Akt (Ser473; cat. no. 4060), Bad (cat. no. 9268), p‑Bad (cat. no. 5284), Bax (cat. no. 14796) and Puma (cat. no. 24633) were purchased from Cell Signaling Technology, Inc. The

(18) In vitro assessment of the efficiency of the PIM‑1 kinase pharmacological inhibitor as a potential treatment for Burkitt's lymphomaOncology LettersJune 29, 2021Mona Alsubaie, Sabine Matou‑nasri, Abdullah Aljedai, Ahmed Alaskar, Hamad Al‑Eidi, Sarah A. Albabtain, Khawlah E. Aldilaijan, Manal Alsayegh, Ibrahim B. Alabdulkareemrabbit primary monoclonal antibodies (1:1,000) directed against phosphorylated (p)-BAD (Ser112; cat. no. 5284), total BAD (cat. no. 9239), pro-caspase-3 (cat. no. 14220) and cleaved caspase-3 (cat. no. 9664) procured

(19) Predictive functional analysis reveals inferred features unique to cervicovaginal microbiota of African women with bacterial vaginosis and high-risk human papillomavirus infectionPLOS ONEJune 18, 2021Harris Onywera, Joseph Anejo-Okopi, Lamech M. Mwapagha, Javan Okendo, Anna-Lise Williamsoncriteria of bacterial vaginosis. BMC Genomics. 2018; 19(Suppl 10):876. https:// doi.org/10.1186/s12864-018-5284-7 PMID: 30598080 22. Ferreira CST, da Silva MG, de Pontes LG, Dos Santos LD, Marconi C. Protein content

(20) CDK4/6 inhibition synergizes with inhibition of P21-Activated Kinases (PAKs) in lung cancer cell linesPLOS ONEJune 17, 2021Gabriela M. Wright, Nick T. Gimbrone, Bhaswati Sarcar, Trent R. Percy, Edna R. Gordián, Fumi Kinose, Natália J. Sumi, Uwe Rix, W. Douglas Cress#3242), PAK1 (Cell Signaling, #2602), PAK2 (Cell Signaling, #2608), phospho Ser112-BAD (Cell Signaling, #5284), BAD (Cell Signaling, #9292). Apoptosis on Celigo Imaging Cytometer Cells were plated with a density

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Phospho-Bad (Ser112) (40A9) Rabbit mAb

Phospho-Bad (Ser112) (40A9) Rabbit mAb from Cell Signaling Technology

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Cell Signaling Technology

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Phospho-Bad (Ser112) (40A9) Rabbit mAb from Cell Signaling Technology

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